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[(2E)-4-hydroxy-2-nonenal--an active component of a new natural antimicrobial substance]
V G Rybin1, D V Kuklev, T M Byval'tseva
1Pacific Research Fishery Center, Vladivostok, Russia. root@tinro.marine.su
Bioorganicheskaia Khimiia
|January 7, 2000
Abstract:
A mixture of water-soluble oxidation products of Sardinops melanosticta sardine oil was found to contain (2E)-4-hydroxy-2-nonenal. This was isolated by column chromatography on silica gel and reversed-phase HPLC. Its structure was elucidated by physicochemical methods. The activity of (2E)-4-hydroxy-2-nonenal against test cultures of Escherichia coli, Staphylococcus aureus, and Bacillus subtilis was about 20% of the total antimicrobial activity of the preparation.