Related Experiment Videos

Effect of malotilate on ethanol-induced gastric mucosal damage in capsaicin-pretreated rats

L Mirossay1, A Kohút, J Mojzis

  • 1Department of Pharmacology, Faculty of Medicine, Safárik University, Kosice, Slovak Republic. mirossay@central.medic.upjs.sk

Physiological Research
|January 7, 2000
PubMed

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Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
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Pathophysiology of Peptic Ulcer Disease: Injurious Factors

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In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds to M3...
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Drugs for Peptic Ulcer Disease: Prostaglandin Analogs as Mucosal Protective Agents

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Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...