Related Experiment Video
Updated: Oct 18, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
[Functional loading tests in nephropathy examination in patients recovering from hemorrhagic fever with renal
Aim:
To characterize nephropathy in patients recovering after hemorrhagic fever with renal syndrome (HFRS) using functional loading tests.
Materials And Methods:
In 65 HFRS convalescents we examined renal function under water deprivation, exercises and studied intraglomerular hemodynamics.
Results:
After 2-month follow-up renal functional reserve was absent in 34% of the convalescents indicating intraglomerular hypertension. Under water deprivation most of the patients showed persistent tubulointerstitial disorders. Submaximal muscular exercises aggravated glomerular and tubular dysfunction manifesting with microalbuminuria, increased excretory beta 2-microglobulin fraction, low concentration reserve.
Conclusion:
Functional loading tests provide more detailed characterization of renal function in HFRS convalescents.
Related Concept Videos
Nephrotic Syndrome II : Assessment and Medical Management
Acute Kidney Injury VI: Nursing Management
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Serum Studies: Renal Function Tests
Acute Kidney Injury I: Introduction
Acute Kidney Injury II: Pathophysiology
