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[The interrelationship of bronchial hyperreactivity and wheezing in children]

O I Lasitsa, A Z Akopian

    Likars'Ka Sprava
    |January 8, 2000
    PubMed

    Insights

    Asthma and wheezing are common in children in Kiev, affecting nearly one-third of those aged 6-14. Bronchial hyperresponsiveness increases with age and can persist despite treatment.

    Area of Science:

    • Pediatric Respiratory Medicine
    • Epidemiology
    • Allergology

    Background:

    • Asthma and wheezing are significant global public health concerns in childhood.
    • Understanding the prevalence and characteristics of these conditions in specific urban populations is crucial for targeted interventions.

    Purpose of the Study:

    • To determine the prevalence of asthma and wheezing symptoms in children aged 6-7 and 13-14 years in Kiev.
    • To assess the prevalence of bronchial hyperresponsiveness in these age groups.
    • To investigate the relationship between age, wheezing, asthma, and bronchial hyperresponsiveness.

    Main Methods:

    • Utilized standardized International Study of Asthma and Allergies in Childhood (ISAAC) protocols.
    • Studied two age cohorts: 6-7 years and 13-14 years, with 400 children in each group.
    • Assessed symptoms of wheezing, asthma diagnosis, and bronchial hyperresponsiveness.

    Main Results:

    • Wheezing prevalence was 29.3% in 6-7 year olds and 25.5% in 13-14 year olds.
    • Asthma prevalence was 30.7% in 6-7 year olds and 31.3% in 13-14 year olds.
    • Bronchial hyperresponsiveness was noted in 56.6% of younger children and 70.2% of older children, increasing with age and persisting despite treatment.

    Conclusions:

    • Asthma and wheezing are highly prevalent in Kiev's pediatric population.
    • Bronchial hyperresponsiveness is common and tends to become persistent with age, indicating a significant underlying airway issue.
    • Findings highlight the need for effective, long-term management strategies for pediatric respiratory conditions in this region.

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