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Capillary affinity gel electrophoresis: new technique for specific recognition of DNA sequence and the mutation
1Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, The University of Tokushima, Shomachi, Japan. ymttbaba@ph.tokushima-u.ac.jp
Journal of Biochemical and Biophysical Methods
|January 8, 2000
Abstract:
The present state of studies on capillary affinity gel electrophoresis, which is a new technique for the specific recognition of a target DNA sequence, is reviewed. This article includes the principle, theory, methods, and applications of this technology. The great potential of capillary affinity gel electrophoresis for the sequence-specific recognition of DNA and the detection of mutations in specific genes is illustrated.