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Recurrent central neurocytoma with marked increase in MIB-1 labelling index
C Christov1, H Adle-Biassette, C Le Guerinel
1Department of Pathology, CHU Henri Mondor, Créteil, France.
British Journal of Neurosurgery
|January 11, 2000
Abstract:
Central neurocytomas (CNs) are characterized by an indolent growth and a low recurrence rate. Cell proliferation has been rarely studied in recurrent CNs despite the growing awareness of its prognostic value. We present a CN that recurred rapidly after a prolonged relapse-free interval showing a 4-fold increase of MIB-1 labelling index.