Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lens development.

J W McAvoy1, C G Chamberlain, R U de Iongh

  • 1Department of Anatomy and Histology, University of Sydney, NSW, Australia. johnmca@anatomy.usyd.edu.au

Eye (London, England)
|January 11, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nox4-mediated ROS production is involved, but not essential for TGFβ-induced lens EMT leading to cataract.

Experimental eye research·2020
Same author

A role for Hippo/YAP-signaling in FGF-induced lens epithelial cell proliferation and fibre differentiation.

Experimental eye research·2018
Same author

Intrinsic and extrinsic regulatory mechanisms are required to form and maintain a lens of the correct size and shape.

Experimental eye research·2016
Same author

Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract.

Experimental eye research·2015
Same author

Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism.

Developmental biology·2013
Same author

Understanding the role of growth factors in embryonic development: insights from the lens.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences·2011
Same journal

Tubing the trabeculectomy: a novel filtration technique.

Eye (London, England)·2026
Same journal

Retinal non-perfusion progression in severe non-proliferative and proliferative diabetic retinopathy over time: INSPIRED study report 2.

Eye (London, England)·2026
Same journal

Macular serpiginous choroiditis versus macular serpiginous-like choroiditis: clinical features, outcomes and prognosis.

Eye (London, England)·2026
Same journal

Association of baseline brain care score with the incidence of age-related eye diseases.

Eye (London, England)·2026
Same journal

A comparative analysis of carbon dioxide versus nitrous oxide as the pressurised gas driving a retinal cryotherapy unit.

Eye (London, England)·2026
Same journal

Determinants of regression kinetics in observed stage 3 retinopathy of prematurity without plus disease.

Eye (London, England)·2026
See all related articles

This review summarizes key molecular mechanisms in eye lens development, covering induction, morphogenesis, differentiation, and growth. It highlights recent advances and future research directions in this complex biological process.

Area of Science:

  • Developmental Biology
  • Molecular Biology
  • Ophthalmology

Background:

  • Lens development is a complex process involving coordinated cellular events.
  • Understanding the molecular basis of lens formation is crucial for addressing developmental eye disorders.

Purpose of the Study:

  • To provide a comprehensive overview of lens development processes.
  • To elucidate the molecular players and regulatory mechanisms governing lens formation.
  • To identify current research frontiers and future challenges in the field.

Main Methods:

  • Review of existing literature on lens development.
  • Analysis of molecular signaling pathways involved in lens morphogenesis.
  • Synthesis of data on genetic and cellular regulation of lens differentiation.

Related Experiment Videos

Main Results:

  • Detailed account of lens induction, morphogenesis, differentiation, and growth.
  • Identification of key molecules and signaling cascades regulating these processes.
  • Summary of recent advancements in understanding the molecular basis of lens development.

Conclusions:

  • Lens development is orchestrated by intricate molecular networks.
  • Further research is needed to fully unravel the complexities of lens formation and related disorders.