Management of hypertension in patients developing end-stage renal failure

I Dasgupta1, R J Madeley, M A Pringle

  • 1Renal Unit, Nottingham City Hospital, UK.

Insights

Hypertension management in patients with end-stage renal failure showed significant deviations from standards. Poor blood pressure control in many patients may have worsened their kidney disease progression.

Area of Science:

  • Nephrology
  • Cardiology
  • Public Health

Background:

  • Hypertension management is crucial for preventing chronic renal failure progression and cardiovascular complications in renal disease patients.
  • Effective blood pressure control is a cornerstone of care for individuals with kidney disease.

Purpose of the Study:

  • To assess the quality of hypertension management in patients initiating dialysis.
  • To identify deviations from established hypertension guidelines in this patient cohort.

Main Methods:

  • A retrospective review of medical records for 145 patients starting dialysis over 3 years.
  • Independent assessment of anonymized data against British Hypertension Society guidelines.
  • Analysis of blood pressure readings and care standards in detection, investigation, referral, and follow-up.

Main Results:

  • 76.4% of patients were hypertensive before end-stage renal failure.
  • Deviations from standards occurred in all care categories: detection (24.3%), investigation (29%), referral (22.4%), and follow-up (17%).
  • Only 45% achieved the recommended diastolic blood pressure of 90 mmHg; 32% had poor control potentially impacting renal failure progression.

Conclusions:

  • Significant gaps exist in hypertension management for patients with end-stage renal disease.
  • Current practices require improvement to optimize blood pressure control and patient outcomes.
  • New strategies are needed to address the identified deficiencies in care.

Related Concept Videos

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
Hypertension V: Nursing Management01:23

Hypertension V: Nursing Management

The nursing management of hypertension involves accurately assessing symptoms, making a comprehensive nursing diagnosis, collaborating with patients to set goals, and implementing targeted interventions to mitigate the condition's impact and improve patient well-being.Comprehensive AssessmentThe initial step in nursing care for hypertension involves a thorough patient assessment. It includes evaluating symptoms such as headaches, dizziness, blurred vision, and previous hypertension episodes.
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...