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Congenital taillessness in AGUS inbred rats
1MRC Experimental Embryology and Teratology Unit, Carshalton, Surrey, United Kingdom.
Laboratory Animals
|January 1, 1984
Abstract:
From a survey of breeding records of the AGUS/ Lac rat colony, 1% of animals weaned were found to lack tails. Post-mortem examination of 5 females showed major skeletal and genital abnormalities. Tailless rats were found more often than expected in 4th and 5th litters. A 'threshold' model of inheritance was postulated with an unknown environmental factor 'triggering' the condition.