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Updated: Sep 30, 2026

Imaging InlC Secretion to Investigate Cellular Infection by the Bacterial Pathogen Listeria monocytogenes
Published on: September 19, 2013
Molecular grouping of Listeria monocytogenes based on the sequence of the inIB gene
Henrik Ericsson, Helle Unnerstad, Jens G Mattsson1
1Department of Food Hygiene, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, PO Box 7009, 750 07 Uppsala and *Department of Parasitology, National Veterinary Institute, PO Box 7073, 750 07 Uppsala, Sweden.
Abstract:
The major part of the gene inlB was sequenced in 24 strains of Listeria monocytogenes belonging to serovars 1/2a, 1/2b, 1/2c, 3b and 4b. A phylogenetic analysis based on the inlB nucleotide sequences showed that strains of serovars 1/2a and 1/2c were closely related, as well as those of serovars 1/2b and 3b. Strains sharing serovar 4b could be divided into two distinct groups. There were differences in amino-acid sequence between all serovars except between serovars 1/2b and 3b. Differences in amino-acid sequence were also seen within each of the serovars 1/2a and 4b. The data presented indicate that the inlB gene may be useful for typing purposes as an alternative or complement to serotyping.
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