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Cholesteryl hemisuccinate exhibits pH sensitive polymorphic phase behavior

I M Hafez1, P R Cullis

  • 1Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of British Columbia, 2146 Health Sciences Mall, Vancouver, B.C., Canada. ismail@interchange.ubc.ca

Biochimica Et Biophysica Acta
|January 13, 2000
PubMed
Summary

Cholesteryl hemisuccinate (CHEMS) exhibits pH-sensitive polymorphism, undergoing fusion below pH 4.3. This pH-dependent behavior of CHEMS is key to the sensitivity of mixed CHEMS and DOPE vesicles.

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