Response functions of proteins
Related Experiment Video
Updated: Oct 18, 2026

Enzymatic Modification and Flow Cytometry Assessment of Yeast Surface Displayed Proteins
Published on: May 30, 2025
1Institut für Physikalische Chemie, Westfälische Wilhelms-Universität, Münster, Germany.
Abstract:
The thermodynamics of protein folding can be studied by a variety of different techniques such as differential scanning calorimetry, differential scanning densimetry and sound velocity measurements. These three methods monitor the different response functions heat capacity, expansion coefficient and compressibility that characterise various aspects of protein dynamics such as equilibrium energy and volume fluctuations and energy-volume correlations. For the development of a comprehensive thermodynamic description of protein behaviour information on these response functions should be combined. As a starting point we provide in the present paper analytical solutions for the determination of the response functions and demonstrate on several examples how to extract a maximum of thermodynamic information on proteins from the measurements of Cp, alpha p and kappa T.
Related Concept Videos
Mechanical Protein Functions
Role of Proteins in the Human Body
Protein Kinases and Phosphatases
Protein kinases
Many proteins in the cell are regulated by phosphorylation, the addition of a phosphate group. A family of enzymes called kinases...
Amplifying Signals via Enzymatic Cascade
Enzyme-linked Receptors
Enzyme-linked Receptors
