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The EMBL Nucleotide Sequence Database. Contributing and accessing data.

P Hingamp1, A E van den Broek, G Stoesser

  • 1EMBL Outstation-The European Bioinformatics Institute (EBI), Hinxton, Cambridge, UK.

Molecular Biotechnology
|January 13, 2000
PubMed
Summary
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The European Molecular Biology Laboratory Nucleotide Sequence Database offers efficient data submission and retrieval for biological sequences. It facilitates international data sharing and provides access to advanced sequence analysis tools.

Area of Science:

  • Molecular Biology
  • Bioinformatics
  • Genomics

Background:

  • The European Molecular Biology Laboratory (EMBL) Nucleotide Sequence Database is a crucial resource for biological data.
  • It collects sequence and annotation data from diverse sources including genome projects, sequencing centers, and individual researchers.

Purpose of the Study:

  • To describe the data submission, curation, and retrieval processes of the EMBL Nucleotide Sequence Database.
  • To highlight the international collaboration and accessibility of the database.

Main Methods:

  • Data submission via the WEBIN tool or established genome project accounts.
  • Curatorial review of submitted data with accession number assignment within two working days.
  • Daily exchange of non-confidential data with DDBJ (Japan) and GenBank (USA).

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Main Results:

  • Efficient data submission and accession number assignment.
  • Seamless international data exchange ensuring up-to-date information.
  • Internet-based access and retrieval using the Sequence Retrieval System (SRS).

Conclusions:

  • The EMBL Nucleotide Sequence Database provides a robust and accessible platform for managing and accessing nucleotide sequences.
  • International collaboration enhances data sharing and availability for the scientific community.
  • Availability of advanced search algorithms facilitates sequence comparison and analysis.