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Related Experiment Videos

Neonatal autopsies: a 10-year experience.

P Kumar1, D B Angst, J Taxy

  • 1Department of Pediatrics, Lutheran General Children's Hospital, Park Ridge, Ill 60068, USA.

Archives of Pediatrics & Adolescent Medicine
|January 13, 2000
PubMed
Summary

Neonatal autopsy rates declined significantly over a decade, yet autopsies provided new diagnoses in 44% of cases, remaining a valuable tool in perinatal medicine.

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Area of Science:

  • Perinatal Medicine
  • Pediatric Pathology
  • Medical Auditing

Background:

  • Neonatal autopsies are crucial for understanding causes of death and improving care.
  • Trends in autopsy rates and diagnostic yield are important for quality assessment.

Purpose of the Study:

  • To analyze trends in neonatal autopsy rates over a decade.
  • To assess the concordance between antemortem and post-mortem diagnoses.
  • To identify patient characteristics influencing autopsy diagnostic yield.

Main Methods:

  • Retrospective review of medical records for all neonatal deaths.
  • Analysis of data including length of stay, imaging, antemortem diagnoses, and autopsy findings.
  • Comparison of autopsy findings with antemortem diagnoses for concordance.

Main Results:

  • Autopsy rate declined from 71.2% to 47.7% over 10 years.
  • New diagnoses were made in 44% of autopsies, with major discordances in 12%.
  • Autopsies yielded more new diagnoses in preterm infants and those with no prenatal care.

Conclusions:

  • A significant decline in neonatal autopsy rates was observed.
  • Neonatal autopsy remains a valuable tool, providing clinically significant data in perinatal medicine.

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