Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A validated three-dimensional computational model of a human knee joint.

G Li1, J Gil, A Kanamori

  • 1Department of Orthopaedic Surgery, University of Pittsburgh, PA 15213, USA. gli@obl.caregroup.harvard.edu

Journal of Biomechanical Engineering
|January 14, 2000
PubMed
Summary

This study developed a validated 3D finite element model of the human knee joint. The model accurately predicts knee kinematics and ligament forces, advancing computational knee biomechanics.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mint3-mediated L1CAM expression in fibroblasts promotes cancer cell proliferation via integrin α5β1 and tumour growth.

Oncogenesis·2017
Same author

Utility of the FIB-4 Index for hepatocarcinogenesis in hepatitis C virus carriers with normal alanine aminotransferase levels.

Journal of viral hepatitis·2015
Same author

The self-fertilizing mangrove killifish Kryptolebias marmoratus as a model fish for aquacultural study.

Communications in agricultural and applied biological sciences·2014
Same author

Paraneoplastic optic neuropathy associated with cerebellar choroid meningioma.

Eye (London, England)·2013
Same author

Long-term efficacy and safety of sitagliptin in the treatment of Japanese Type 2 diabetes (ASSET-K1) to a target of HbA1c <7%.

Journal of endocrinological investigation·2013
Same author

Correlation of serum ribavirin concentration with pretreatment renal function estimates in patients with chronic hepatitis C receiving combination antiviral therapy with peginterferon and ribavirin.

Journal of viral hepatitis·2008

Area of Science:

  • Biomechanics
  • Computational modeling
  • Orthopedics

Background:

  • Accurate modeling of knee joint biomechanics is crucial for understanding injury mechanisms and developing treatments.
  • Previous models often lacked detailed validation or comprehensive representation of all knee structures.

Purpose of the Study:

  • To develop and validate a three-dimensional finite element model of the human tibio-femoral joint.
  • To assess the contribution of menisci to accurate knee kinematics prediction.

Main Methods:

  • Obtained knee geometry from MRI scans of a cadaveric specimen.
  • Validated the finite element model (FEM) against experimental kinematic data from robotic testing.
  • Modeled cartilage as elastic, ligaments as nonlinear springs, and menisci as equivalent-resistance springs.

Related Experiment Videos

Main Results:

  • The validated FEM accurately predicted knee kinematics under anterior-posterior tibial loads.
  • The model successfully simulated in-situ ligament forces in response to tibial moments.
  • Equivalent-resistance springs for menisci were essential for accurate kinematic predictions.

Conclusions:

  • The developed finite element model is a valuable tool for analyzing human knee joint function.
  • This methodology represents a significant step towards creating more sophisticated computational knee models.
  • Accurate representation of meniscal behavior is critical for reliable knee biomechanical simulations.