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Probiotics and infectious diarrhea.

J Saavedra1

  • 1Johns Hopkins Medical Center, Baltimore, Maryland 21287, USA.

The American Journal of Gastroenterology
|January 14, 2000
PubMed
Summary

Probiotic agents show promise in managing and preventing various diarrheal diseases in children. Specific strains like Lactobacillus GG and Saccharomyces boulardii are effective for acute diarrhea, while Bifidobacteria may offer prophylaxis.

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Area of Science:

  • Gastroenterology
  • Pediatrics
  • Microbiology

Background:

  • Diarrheal diseases pose a significant health challenge in infants and children.
  • Probiotic agents are increasingly explored for their therapeutic and prophylactic potential in gastrointestinal health.

Purpose of the Study:

  • To review the efficacy of various probiotic agents in the management of diarrheal diseases in pediatric populations.
  • To identify specific probiotic strains and their applications in preventing and treating different types of diarrhea.

Main Methods:

  • Literature review of studies investigating probiotic use for diarrhea in children.
  • Analysis of clinical trial data on specific probiotic agents like Lactobacillus GG, Lactobacillus reuteri, and Saccharomyces boulardii.
  • Examination of prophylactic effects of probiotics, such as Bifidobacteria, in infant feeding.

Main Results:

  • Lactobacillus GG, Lactobacillus reuteri, and Saccharomyces boulardii show therapeutic benefits for acute diarrhea in children.
  • Bifidobacteria may serve as prophylactic agents against acute diarrheal diseases when supplemented in infant diets.
  • Probiotic efficacy is most pronounced against viral (rotaviral) diarrhea in pediatric populations, suggesting an immunological basis.

Conclusions:

  • Probiotic agents are valuable additions to the treatment strategies for gastrointestinal issues in infants and children.
  • Further research is needed to generalize findings due to variations in agents, doses, and populations studied.
  • The role of probiotics in preventing and managing pediatric diarrhea is significant and expanding.

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