Related Experiment Video
Updated: Aug 16, 2026

Murine Salivary Functional Assessment via Pilocarpine Stimulation Following Fractionated Radiation
Published on: May 4, 2018
Salivary flow and oral complaints in adult dental patients
1School of Dentistry, Umeå University, Sweden. maud.bergdahl@oralbio.umu.se
Abstract:
Saliva plays an important role in maintaining oral health and functions. In the present study, unstimulated and stimulated whole salivary flow and various oral complaints were surveyed in 1427 individuals, 669 men (47%) and 758 women (53%). These individuals, aged 20 to 69 years and from different socioeconomic backgrounds, were recruited from 2000 randomly selected men and women in the register of the public dental health service in northern Sweden. The unstimulated salivary flow rate ranged from 0 to 2.07 mL/min (mean 0.33+/-SD 0.26) for men, and from 0 to 1.35 mL/min (mean 0.26+/-SD 0.21) for women. The stimulated salivary flow rate ranged from 0.17 to 7.3 mL/min (mean 2.50+/-SD 1.06) for men, and from 0 to 6.40 mL/min (mean 2.02+/-SD 0.93) for women. Women over 55 years of age had a reduced unstimulated salivary flow (P<0.05). Individuals with many teeth had a higher stimulated salivary flow than those with fewer teeth (P<0.001). Male smokers had a lower unstimulated salivary flow than male non-smokers (P<0.05). Women with oral lesion complaints had a lower unstimulated salivary flow (P<0.05), and women with burning mouth had a lower stimulated salivary flow (P<0.01). Individuals with subjective oral dryness had reduced salivary flow, both unstimulated (men P<0.01, women P<0.001) and stimulated (P<0.001). Subjective oral dryness was associated with complaints of burning mouth (P<0.001), muscle pain (P<0.01), taste disturbances (P<0.01), and dry eyes (P<0.05). Individuals with subjective oral dryness had fewer teeth than individuals with no such complaints (P<0.001). Information regarding salivary flow rate in adults is important in understanding and evaluating the relationship between salivary flow and various types of oral complaints in patients.
Related Concept Videos
Oral Cavity
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
Salivary Glands and Saliva
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Assessment of the Mouth
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
The Oral Microbiota

