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Relating axonal injury to functional recovery in MS
H Reddy1, S Narayanan, P M Matthews
1Department of Neurology and Neurosurgery, Montreal-Neurological Institute, McGill University, Canada.
Neurology
|January 15, 2000
Abstract:
A patient was followed after the new onset of hemiparesis from relapse of MS with serial MR spectroscopy and functional MRI. The association of clinical improvement with recovery of N-acetylaspartate, a marker of neuronal integrity, and progressive reduction of abnormally large functional MRI cortical activation with movement demonstrates that dynamic reorganization of the motor cortex accompanies remission of MS.