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The SIBDQ: further validation in ulcerative colitis patients
S W Han1, W Gregory, D Nylander
1Academic Department, University of Newcastle Regional School of Medicine, North Tyneside General Hospital, North Shields.
The American Journal of Gastroenterology
|January 19, 2000
Summary
A new short form of the Inflammatory Bowel Disease Questionnaire (SIBDQ) was developed for ulcerative colitis patients. This colitis-specific SIBDQ showed high predictive value but no clear advantage over the original SIBDQ for clinical practice.
Area of Science:
- Gastroenterology
- Clinical Research
- Health Outcomes
Background:
- The Inflammatory Bowel Disease Questionnaire (IBDQ) assesses quality of life in inflammatory bowel disease (IBD) patients.
- A short form (SIBDQ) was previously developed for Crohn's disease, but ulcerative colitis patients may benefit from a tailored instrument.
Purpose of the Study:
- To design and validate a SIBDQ specifically for ulcerative colitis patients.
- To compare the performance of the new ulcerative colitis SIBDQ with the existing Crohn's disease SIBDQ.
Main Methods:
- 122 ulcerative colitis patients were recruited for initial sample analysis.
- Linear regression modeling identified 10 items that best predicted the total IBDQ score.
- The newly developed colitis SIBDQ and the Crohn's SIBDQ were compared using the total IBDQ score in additional patient cohorts.
Main Results:
- Ten items explained 97% of the variance in the total IBDQ score.
- Only three items were common between the colitis and Crohn's SIBDQ versions.
- Both SIBDQ versions demonstrated high predictive accuracy (R2 > 0.95), with the colitis version showing superior internal consistency.
Conclusions:
- A SIBDQ for ulcerative colitis was developed, but it did not show a clear advantage over the original SIBDQ.
- Further research is needed to establish the utility of the SIBDQ in routine clinical practice for ulcerative colitis management.