Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Collating collagenous colitis cases.

C M Surawicz1

  • 1University of Washington, Seattle, USA.

The American Journal of Gastroenterology
|January 19, 2000
PubMed
Summary
This summary is machine-generated.

Flexible sigmoidoscopy is adequate for diagnosing most collagenous colitis cases. Biopsy site impacts diagnostic yield, with the transverse colon showing the highest detection rate for subepithelial collagen thickness.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Infectious causes of chronic diarrhea.

Gastroenterology clinics of North America·2001
Same author

The search for a better treatment for recurrent Clostridium difficile disease: use of high-dose vancomycin combined with Saccharomyces boulardii.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2000
Same author

Pseudomembranous colitis: an update.

Canadian journal of gastroenterology = Journal canadien de gastroenterologie·2000
Same author

Behaviour of Saccharomyces boulardii in recurrent Clostridium difficile disease patients.

Alimentary pharmacology & therapeutics·1999
Same author

Etiological role of mycobacterium in Crohn's disease: An assessment of the literature.

Digestive diseases (Basel, Switzerland)·1999
Same author

Pseudomembranous colitis: causes and cures.

Digestion·1999
Same journal

ACG Clinical Guideline: Colonic Diverticulitis.

The American journal of gastroenterology·2026
Same journal

Inter and intra-observer agreement for the LST Classification in Large (>2cm) Colorectal Laterally Spreading Tumours.

The American journal of gastroenterology·2026
Same journal

The Safety and Effectiveness of Early Anti-Tumor-Necrosis-Factor Therapy for Penetrating Crohn's Disease Complications in Children.

The American journal of gastroenterology·2026
Same journal

Continuing Medical Education Questions: September 2024.

The American journal of gastroenterology·2026
Same journal

Continuing Medical Education Questions: September 2024.

The American journal of gastroenterology·2026
Same journal

Continuing Medical Education Questions: September 2024.

The American journal of gastroenterology·2026
See all related articles

Area of Science:

  • Gastroenterology
  • Histopathology

Background:

  • Collagenous colitis is a condition characterized by chronic diarrhea.
  • Diagnosis relies on identifying subepithelial collagen layer thickening in colonic biopsies.

Purpose of the Study:

  • To clarify the relationship between diagnostic histology and biopsy site in collagenous colitis.
  • To determine the optimal biopsy location for diagnosing collagenous colitis.

Main Methods:

  • Retrospective review of 56 collagenous colitis cases diagnosed between 1980 and 1993.
  • Histological evaluation of nearly 300 colonic biopsies.
  • Analysis of subepithelial collagen thickness in relation to biopsy location.

Main Results:

  • Diagnostic subepithelial collagen thickness varied across different colon segments.

Related Experiment Videos

  • Highest diagnostic yield was observed in the transverse colon (83%) and right colon (70%).
  • A collagen thickness threshold greater than 30 micrometers increased diagnostic confidence.

    • Conclusions:

    • Flexible sigmoidoscopy is generally sufficient for diagnosing collagenous colitis.
    • Colonoscopy may be necessary for cases with mild or focal findings distally.
    • Biopsy site selection can optimize diagnostic accuracy for collagenous colitis.