Hereditary hemorrhagic telangiectasia with gingival lesion. Review and case reports

A case of hereditary, hemorrhagic telangiectasia is described which has been under observation for more than 8 years. The clinical findings are discussed; light microscopic and electron microscopic findings as well as current research for a causative mechanism and recommended therapy are reviewed. The patient exhibited gingival telangiectatic participation. Another, even more severe case of this disease showed repeated, severe hemorrhage from mucosal lesions in the region of the incisive papilla, severe internal bleeding from the nasal mucosa and the gut and several punctate gingival telangiectases. The occurance of gingival lesions may not be as rare as thought. Such lesions may simply be rather inconspicuous.