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Xanthoma disseminatum with respiratory tract involvement and fatal outcome
C W Davies1, P Marren, M C Juniper
1Osler Chest Unit, Churchill Hospital, Oxford Radcliffe Trust, Oxford OX3 7LJ, UK.
Abstract:
Xanthoma disseminatum (XD) is a rare mucocutaneous xanthomatosis classified as a benign form of non-Langerhans' cell histiocytosis. The case history is presented of a 61 year old woman with XD who developed dyspnoea and spirometric features of airflow obstruction. Bronchoscopy and computed tomography confirmed involvement of the large and medium sized bronchi and she subsequently died from acute respiratory failure. The post-mortem findings and the importance of respiratory tract disease in this unusual condition are discussed.
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