Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An unusually aggressive trichoblastoma.

E W Cowen1, K F Helm, E M Billingsley

  • 1Department of Medicine/Section of Dermatology, The Pennsylvania State University College of Medicine, The Milton S. Hershey Medical Center, Penn State Geisenger Health System, Hershey 17033, USA.

Journal of the American Academy of Dermatology
|January 21, 2000
PubMed
Summary

Trichogenic tumors, like trichoblastoma, are typically benign neoplasms. This case highlights a large, invasive trichoblastoma with features overlapping basal cell carcinoma, necessitating Mohs surgery.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of cutaneous squamous cell carcinoma: A literature review and update.

Journal of the American Academy of Dermatology·2025
Same author

Image Gallery: Primary cutaneous Rosai-Dorfman disease.

The British journal of dermatology·2019
Same author

Tumor-induced osteomalacia in association with PTEN-negative Cowden syndrome.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2018
Same author

Oral disease profiles in chronic graft versus host disease.

Journal of dental research·2015
Same author

NIH response criteria measures are associated with important parameters of disease severity in patients with chronic GVHD.

Bone marrow transplantation·2014
Same author

Malnutrition in patients with chronic GVHD.

Bone marrow transplantation·2014

Area of Science:

  • Dermatopathology
  • Surgical Oncology

Background:

  • Trichogenic tumors originate from hair germ cells and typically display benign behavior.
  • Distinguishing between benign trichogenic tumors and malignant neoplasms can be challenging.
  • Invasive variants necessitate aggressive treatment strategies.

Observation:

  • A case report of a large, invasive trichoblastoma is presented.
  • The tumor required Mohs micrographic surgery for complete excision.
  • Immunohistochemical analysis revealed similarities with basal cell carcinoma.

Findings:

  • The invasive trichoblastoma demonstrated overlapping immunohistochemical features with basal cell carcinoma.
  • Mohs micrographic surgery was effective for the complete removal of the large, invasive tumor.

Related Experiment Videos

  • This case underscores the potential for aggressive behavior in trichogenic tumors.

    • Implications:

    • Highlights the importance of accurate diagnosis and classification of trichogenic tumors.
    • Suggests potential shared pathways or differentiation markers between trichoblastoma and basal cell carcinoma.
    • Emphasizes the role of Mohs surgery in managing complex or invasive cutaneous neoplasms.