Related Experiment Videos
[The ocular changes in patients on chronic dialysis]
1Clinica Oftalmologică Craiova.
Oftalmologia (Bucharest, Romania : 1990)
|January 21, 2000
Summary
This study on chronic renal failure patients undergoing hemodialysis found reduced tear production and specific fundus optic changes. These findings correlate with decreased circulatory debit during dialysis.
Area of Science:
- Ophthalmology
- Nephrology
- Uremic Syndrome
Background:
- Chronic renal failure (CRF) impacts multiple organ systems, including ocular health.
- Hemodialysis is a critical treatment for CRF, but its systemic effects require thorough investigation.
- Ocular manifestations in CRF patients, particularly during dialysis, are not fully understood.
Observation:
- The study examined 30 CRF patients undergoing hemodialysis, assessing lacrimal secretion, lacrimal urea levels, and fundus optic changes.
- Ophthalmologic examinations, including Schirmer I-test and lacrimal urea measurement, were performed before and after hemodialysis.
- Fundus examinations revealed a pale optic disc with filiform arterioles, indicative of reduced circulatory debit, more pronounced pre-dialysis.
Findings:
- Patients exhibited lacrimal hyposecretion (reduced tear production).
- Lacrimal urea levels were lower than blood urea levels, showing concordance with urea clearance.
- A pale fundus and constricted arterioles were observed, suggesting decreased ocular blood flow during hemodialysis.
Implications:
- Findings suggest a link between hemodialysis, ocular hemodynamics, and lacrimal function in CRF patients.
- Monitoring ocular changes may offer insights into systemic circulatory adjustments during dialysis.
- Further research could explore therapeutic interventions targeting ocular complications in CRF.