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Related Experiment Videos

A prospective, randomized multicenter study comparing APD and CAPD treatment.

S Bro1, J B Bjorner, P Tofte-Jensen

  • 1Department of Nephrology, Rigshospitalet, Copenhagen, Denmark.

Peritoneal Dialysis International : Journal of the International Society for Peritoneal Dialysis
|January 21, 2000
PubMed
Summary
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Automated peritoneal dialysis (APD) offers patients more time for work and social activities compared to continuous ambulatory peritoneal dialysis (CAPD). While APD has higher daily costs, it may be a reasonable choice for selected patients.

Area of Science:

  • Nephrology
  • Renal Replacement Therapy
  • Quality of Life Studies

Background:

  • Maintenance dialysis aims to enhance patient survival, reduce morbidity, and improve quality of life.
  • Peritoneal dialysis modalities include automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD).

Purpose of the Study:

  • To compare the quality of life and clinical outcomes of APD versus CAPD.
  • To evaluate therapy costs associated with APD and CAPD.

Main Methods:

  • A prospective, randomized multicenter study involving 34 patients with high or high-average peritoneal transport characteristics.
  • Patients were randomized to either APD or CAPD for 6 months.
  • Quality of life was assessed using the SF-36 questionnaire and disease-specific questions; clinical outcomes and costs were also evaluated.

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Main Results:

  • Patients on APD reported significantly more time for work, family, and social activities (p < 0.001).
  • A trend towards less discomfort from dialysis fluid was observed in the APD group, though sleep problems were more frequent.
  • No significant differences in dialysis-related hospital days or complication rates were found between APD and CAPD.
  • Daily running costs were higher for APD ($75) compared to CAPD ($61).

Conclusions:

  • APD may enable selected patients to remain vocationally and socially active.
  • The additional cost of APD may be justified if it supports patient engagement in work and social life.