Related Experiment Video
Updated: Aug 7, 2026

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
Published on: January 19, 2024
Spontaneous bullae over laser resurfaced skin
1Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Facial bullae, or blisters, can occur after carbon dioxide laser skin resurfacing. Potent topical corticosteroids effectively treated these rare laser resurfacing complications.
Area of Science:
- Dermatology
- Laser Surgery
- Aesthetic Medicine
Background:
- Carbon dioxide (CO2) laser skin resurfacing is a widely used dermatological procedure for facial rejuvenation.
- While generally safe, potential complications require ongoing monitoring and reporting.
- Understanding adverse events is crucial for patient safety and procedural refinement.
Observation:
- Two cases of facial bullae (blisters) developed after full-face CO2 laser resurfacing were observed.
- The bullae appeared in the post-operative period, requiring clinical attention.
- The exact etiology of the bullae formation remained undetermined.
Findings:
- Both patients with facial bullae post-CO2 laser resurfacing showed a positive response to potent topical corticosteroid therapy.
- Prompt treatment with corticosteroids led to the resolution of the bullae.
- This suggests a potential inflammatory or immune-mediated component to the complication.
Implications:
- Facial bullae represent a rare but notable complication of CO2 laser skin resurfacing.
- Physicians performing laser resurfacing should be aware of this potential adverse event.
- The successful treatment with topical corticosteroids provides a therapeutic option for managing this complication.
More Related Videos
03:47Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
04:43Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
Published on: May 23, 2025
Related Concept Videos
Clinical Applications of Epidermal Stem Cells
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...