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Updated: Oct 18, 2026

Laparoscopic S7 Hepatectomy with Positive Fluorescence Staining
Published on: May 9, 2025
Hepatocellular carcinoma metastasizing to the orbit diagnosed by fine needle aspiration cytology
R A Scolyer1, D M Painter, C G Harper
1Department of Anatomical Pathology, Royal Prince Alfred Hospital, NSW, Australia.
Abstract:
Hepatocellular carcinoma (HCC) rarely metastasizes to the orbit. We report a case of a 78-year-old man with a past history of HCC, who presented with a periorbital mass, which was diagnosed as metastatic HCC by fine needle aspiration cytology (FNAC) and subsequently confirmed on excision biopsy. The cytological, histopathological and immunohistochemical findings are presented and the differential diagnosis is discussed. To our knowledge there has been no previously reported case of HCC metastatic to the orbit diagnosed by FNAC.