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Vitamin A deficiency disorders.

D S McLaren1

  • 1International Centre of Eye Health, Institute of Ophthalmology, London.

Journal of the Indian Medical Association
|January 22, 2000
PubMed
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Vitamin A deficiency disorders (VADD) cause childhood blindness and mortality globally. Prevention strategies like supplementation and food fortification are crucial for public health, though treatment access remains a challenge.

Area of Science:

  • Public Health
  • Nutrition
  • Ophthalmology

Background:

  • Xerophthalmia, stemming from vitamin A deficiency, is a leading cause of childhood blindness worldwide.
  • Vitamin A deficiency disorders (VADD) encompass a spectrum of clinical effects, including increased mortality.
  • Existing classification and prevalence criteria aid in identifying VADD as a public health concern.

Purpose of the Study:

  • To review the global prevalence and public health impact of VADD.
  • To discuss the limitations in current treatment accessibility for VADD.
  • To evaluate various prevention strategies for VADD, including supplementation, food fortification, infection control, and dietary improvements.

Main Methods:

  • Review of global prevalence data on VADD.
Keywords:
BiologyBlindnessDeficiency DiseasesDiseasesMicronutrientsNutrition DisordersOphthalmological EffectsPhysiologyProgress ReportTreatmentVitamin AVitaminsWorld

Related Experiment Videos

  • Analysis of established treatment protocols for xerophthalmia.
  • Discussion of advantages and disadvantages of different prevention methods.

    • Main Results:

    • Global prevalence of VADD is well-documented, with ongoing data collection by the WHO.
    • Treatment for established VADD cases is available, but concentrated vitamin A sources are often scarce in clinical settings.
    • Prevention methods such as high-dose supplementation, food fortification, infection control, and dietary enhancement are key.

    Conclusions:

    • While treatment exists, prevention is paramount for combating VADD.
    • A multi-faceted approach combining supplementation, fortification, infection control, and dietary improvements is necessary.
    • Further research into VADD pathogenesis may elucidate why some individuals are more susceptible.