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Leukoencephalopathy in multiple myeloma: two case reports
C Lebrun1, S Chanalet, M Frenay
1Service de Neurologie, Hôpital Pasteur, Nice, France.
Abstract
Background:
No case of leukoencephalopathy has been reported associated with multiple myeloma.
Patients:
We report on two patients with a very rare association of leukoencephalopathy and multiple myeloma revealed by cognitive impairment.
Results:
Chemotherapy has improved neurological and biological signs. Radiological abnormalities have been stabilized.
Conclusion:
The authors suggest that leukoencephalopathy is probably a direct cerebral expression of malignant gammopathy.