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Published on: June 27, 2012
Cyclooxygenases in reproductive medicine and biology
1Department of Obstetrics and Gynecology, Ohio State University, College of Medicine and Public Health, Columbus 43210, USA. kniss.1@osu.edu
Abstract:
This review focuses on the role of cyclooxygenases in reproductive medicine and biology. The cyclooxygenase enzymes catalysis the role-limiting reactions for prostaglandins and thromboxane synthesis. Two separate isoforms, COX-1 and COX-2, are present, and differences in their roles are discussed in the context of inflammation and parturition.
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