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Related Experiment Videos

Dermal intravascular leiomyosarcoma in a cat.

M C Jacobsen1, B A Valentine

  • 1Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA.

Veterinary Pathology
|January 22, 2000
PubMed
Summary

A cat developed a rare dermal intravascular leiomyosarcoma, a type of smooth muscle tumor, in its hind foot. This tumor recurred after surgical removal, highlighting its aggressive nature.

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Area of Science:

  • Veterinary Pathology
  • Oncology
  • Dermatology

Background:

  • Subcutaneous tumors in felines can present diagnostic challenges.
  • Vascular-associated neoplasms require careful histological evaluation.

Observation:

  • A domestic shorthaired cat presented with recurrent subcutaneous tumors on the left hind foot.
  • Tumors were located between phalanges and on the medial aspect of a phalanx.

Findings:

  • Histopathology revealed solid masses of spindle and round cells within endothelial-lined vessels.
  • Immunohistochemistry showed positivity for smooth muscle actin and vimentin.
  • Tumor cells were negative for cytokeratin, S-100, desmin, synaptophysin, factor VIII-related antigen, and neuron-specific enolase, supporting a smooth muscle origin.

Implications:

  • The diagnosis of dermal intravascular leiomyosarcoma was confirmed.
  • This case underscores the importance of thorough histopathological and immunohistochemical analysis for accurate diagnosis of feline cutaneous tumors.
  • Recurrence suggests the need for vigilant monitoring and potentially aggressive treatment strategies for this rare condition.

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