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Prostate cancer: MR imaging and thermometry during microwave thermal ablation-initial experience
J C Chen1, J A Moriarty, J A Derbyshire
1Department of Medical Imaging, Toronto Hospital and the University of Toronto, Ontario, Canada.
Radiology
|January 22, 2000
Summary
Magnetic resonance (MR) imaging effectively guided microwave thermoablation for recurrent prostate cancer. This technique accurately mapped temperature changes, correlating well with tissue damage for precise treatment.
Area of Science:
- Oncology
- Medical Imaging
- Interventional Radiology
Background:
- Locally recurrent prostate carcinoma presents treatment challenges.
- Minimally invasive thermal ablation techniques offer potential therapeutic options.
- Accurate real-time monitoring is crucial for effective thermal ablation.
Purpose of the Study:
- To evaluate the feasibility of using magnetic resonance (MR) imaging for guiding percutaneous interstitial microwave thermoablation.
- To assess the accuracy of MR imaging in monitoring tissue temperature changes during the procedure.
- To correlate MR imaging findings with thermal ablation outcomes in recurrent prostate cancer.
Main Methods:
- Percutaneous interstitial microwave thermoablation was performed on locally recurrent prostate carcinoma.
- Magnetic resonance (MR) imaging, utilizing a rapid gradient-echo technique, continuously guided the procedure.
- Proton-resonance shift was used to derive tissue temperature changes from MR phase images.
Main Results:
- Thermally devitalized regions demonstrated strong correlation with MR phase image findings.
- MR imaging-derived temperatures showed a linear relationship with fluoroptic tissue temperatures.
- The technique provided accurate, real-time temperature monitoring during thermoablation.
Conclusions:
- Magnetic resonance (MR) imaging is a viable tool for guiding percutaneous microwave thermoablation.
- MR imaging enables precise monitoring of thermal effects, ensuring accurate ablation zones.
- This imaging modality enhances the safety and efficacy of thermal ablation for recurrent prostate cancer.