Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Retinal detachment in ocular toxoplasmosis.

L H Bosch-Driessen1, S Karimi, J S Stilma

  • 1Donders Institute of Ophthalmology, University Hospital Utrecht, The Netherlands.

Ophthalmology
|January 27, 2000
PubMed
Summary

Ocular toxoplasmosis can lead to retinal detachment and breaks, particularly in those with severe inflammation and myopia. Early retinal exams are crucial for patients with ocular toxoplasmosis to prevent vision loss.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Targeted inhibition of mu-opioid receptors in neuronal subpopulations by membrane-tethered Naloxo-DART antagonists.

Cell chemical biology·2025
Same author

Assessment of conjunctival, episcleral and scleral thickness in healthy individuals using anterior segment optical coherence tomography.

Acta ophthalmologica·2023
Same author

The additive effect of intravitreal dexamethasone combined with bevacizumab in refractory diabetic macular edema.

Journal francais d'ophtalmologie·2023
Same author

Acetazolamide and bevacizumab combination therapy versus bevacizumab monotherapy in macular edema secondary to retinal vein occlusion.

Journal francais d'ophtalmologie·2023
Same author

Subconjunctival Rituximab Administration for the Treatment of Scleritis.

Ocular immunology and inflammation·2022
Same author

Clinical Relevance of Autoantibodies and Inflammatory Parameters in Non-infectious Scleritis.

Ocular immunology and inflammation·2021

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Retinal Diseases

Background:

  • Ocular toxoplasmosis is an inflammatory condition of the eye caused by the parasite *Toxoplasma gondii*.
  • Retinal breaks and detachment are potential complications that can significantly impact vision.

Purpose of the Study:

  • To investigate the clinical course and prognosis of retinal breaks and detachment in patients diagnosed with ocular toxoplasmosis.
  • To identify risk factors associated with these retinal complications.

Main Methods:

  • A retrospective cross-sectional observational study was conducted.
  • Data from 150 consecutive patients with ocular toxoplasmosis treated between 1990 and 1997 were analyzed.
  • Risk factors including age, myopia, inflammation severity, and treatment history were examined in relation to retinal abnormalities.

Related Experiment Videos

Main Results:

  • Retinal detachment occurred in 6% of patients, and retinal breaks in 5%.
  • Severe intraocular inflammation preceded retinal detachment or breaks in affected patients.
  • Myopia was significantly more prevalent in patients with retinal complications compared to those without.

Conclusions:

  • Retinal detachment in ocular toxoplasmosis carries a poor functional prognosis, with legal blindness occurring in half of the affected cases.
  • Ocular toxoplasmosis patients, especially those with myopia and severe inflammation, require thorough retinal examinations.
  • Prompt diagnosis and management are essential to mitigate vision-threatening complications.