Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Urticarial vasculitis.

J J Wisnieski1

  • 1Louis Stokes Cleveland Department of Veterans Affairs Medical Center, OH 44106, USA. jjw@po.cwru.edu

Current Opinion in Rheumatology
|January 27, 2000
PubMed
Summary
This summary is machine-generated.

Urticarial vasculitis, often misdiagnosed as chronic idiopathic urticaria, affects about 10% of patients. Early diagnosis is crucial as it can indicate serious underlying systemic diseases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Homozygous single nucleotide polymorphism of the complement C1QA gene is associated with decreased levels of C1q in patients with subacute cutaneous lupus erythematosus.

Lupus·2003
Same author

C1 inhibitor: analysis of the role of amino acid residues within the reactive center loop in target protease recognition.

Journal of immunology (Baltimore, Md. : 1950)·2001
Same author

The globular heads of C1q specifically recognize surface blebs of apoptotic vascular endothelial cells.

Journal of immunology (Baltimore, Md. : 1950)·2001
Same author

Clinical image: cutaneous ulceration in type II cryoglobulinemia.

Arthritis and rheumatism·1998
Same author

Antibodies to C1q in systemic lupus erythematosus: characteristics and relation to Fc gamma RIIA alleles.

Kidney international·1997
Same author

IgG autoantibodies to complement C1q in pediatric-onset systemic lupus erythematosus.

Clinical and experimental rheumatology·1997

Area of Science:

  • Dermatology
  • Immunology
  • Internal Medicine

Background:

  • Chronic or recurrent urticarial lesions present diagnostic and therapeutic challenges in clinical practice.
  • Most cases are diagnosed as chronic idiopathic urticaria, with a subset having autoimmune triggers like IgG autoantibodies.
  • Urticarial vasculitis is an underdiagnosed condition, affecting a small percentage of patients with chronic urticarial lesions.

Purpose of the Study:

  • To differentiate urticarial vasculitis from chronic idiopathic urticaria.
  • To highlight the potential for significant morbidity and association with systemic illness in urticarial vasculitis.
  • To emphasize the importance of thorough evaluation for underlying conditions in suspected urticarial vasculitis cases.

Main Methods:

  • Review of clinical presentations and diagnostic challenges in urticarial lesions.

Related Experiment Videos

  • Distinguishing features between chronic idiopathic urticaria and urticarial vasculitis.
  • Assessment of potential underlying systemic diseases associated with urticarial vasculitis.

    • Main Results:

    • Approximately 10% of patients with chronic urticarial lesions are diagnosed with urticarial vasculitis.
    • Urticarial vasculitis can be associated with significant morbidity and serious underlying systemic illnesses.
    • Autoimmune factors (IgG autoantibodies to IgE receptor or IgE) are implicated in 30% of chronic idiopathic urticaria cases.

    Conclusions:

    • Urticarial vasculitis requires careful diagnostic consideration due to its potential severity.
    • Systematic evaluation for systemic diseases such as lupus erythematosus, Sjögren's syndrome, and cryoglobulinemia is essential.
    • Timely diagnosis and management of urticarial vasculitis are critical for patient outcomes.