Related Experiment Video
Updated: Aug 17, 2026

Identifying the Binding Proteins of Small Ligands with the Differential Radial Capillary Action of Ligand Assay (DRaCALA)
Published on: March 19, 2021
5-(beta-Cyclodextrinylamino)-5-Deoxy-alpha-D-Riboses as Models for Nuclease, Ligase, Phosphatase, and Phosphorylase
1Department of Molecular Science and Technology Ajou University, Suwon 442-749 (Korea).
Abstract:
beta-Cyclodextrin derivatives crowned with ribose rings (such as 1) catalyzed the hydrolysis, esterification, and phosphorylation of catechol-derived phosphate esters. The vicinal cis-diols on the ribose groups appear to play a major role in the catalytic activity of these enzyme models by the formation of hydrogen bonds which activate the phosphorus atom to nucleophilic attack.
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