Jove
Visualize
Contact Us

Related Experiment Videos

Dual task performance in HIV-1 infection.

C H Hinkin1, S A Castellon, D J Hardy

  • 1Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, CA 90024, USA. chinkin@ucla.edu

Journal of Clinical and Experimental Neuropsychology
|January 29, 2000
PubMed
Summary

HIV-1 infection impairs divided attention. HIV-infected individuals showed greater performance declines on dual tasks, indicating difficulties in processing multiple stimuli simultaneously.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multilaboratory Comparison of Omadacycline MIC Test Strip to Broth Microdilution MIC against Gram-Negative, Gram-Positive, and Fastidious Bacteria.

Journal of clinical microbiology·2021
Same author

Scalable Molecular Dynamics with NAMD on the Summit System.

IBM journal of research and development·2020
Same author

Multilab evaluation of delafloxacin MIC Test Strip against Gram-negative and Gram-positive organisms.

Diagnostic microbiology and infectious disease·2019
Same author

Cognitive rehabilitation group intervention for breast cancer survivors: results of a randomized clinical trial.

Psycho-oncology·2015
Same author

Analysis of the peptide carrier in the scutellum of barley embryos by photoaffinity labelling.

Planta·2013
Same author

The association between pro-inflammatory cytokines, regional cerebral metabolism, and cognitive complaints following adjuvant chemotherapy for breast cancer.

Brain imaging and behavior·2013
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Neuroscience
  • Infectious Diseases
  • Psychology

Background:

  • Human Immunodeficiency Virus type 1 (HIV-1) infection is known to affect cognitive functions.
  • Previous research suggests potential impacts on attention and processing speed.

Purpose of the Study:

  • To investigate the effects of HIV-1 infection on dual task performance.
  • To assess cognitive deficits in divided attention and simultaneous processing in individuals with HIV-1.

Main Methods:

  • Fifty HIV-infected individuals and 20 controls performed auditory and visual reaction time (RT) tasks under single and dual task conditions.
  • Performance decrements were compared between groups.
  • Association with Stroop task performance was examined.

Main Results:

  • HIV-infected individuals showed significantly greater performance decrements on both simple and choice RT dual tasks compared to controls.
  • This dual task deficit correlated with poorer performance on the Stroop interference task.
  • A trend suggested greater deficits in patients with AIDS compared to pre-AIDS individuals.

Conclusions:

  • HIV-1 infection leads to significant deficits in divided attention and the ability to process competing stimuli simultaneously.
  • These findings suggest disruption of the anterior attentional system in HIV-1 infection.
  • Cognitive impairments in dual tasking may be a key indicator of neurological involvement in HIV-1.

Related Experiment Videos