Related Experiment Video
Updated: Aug 9, 2026

07:29
Intravascular Delivery of Biologics to the Rat Kidney
Published on: September 1, 2016
Renovascular disease
S C Rankin1, A J Saunders, G J Cook
1Department of Radiology, Guy's Hospital, Guy's and St.Thomas' Trust, London, UK.
Clinical Radiology
|January 29, 2000
Summary
Angiography is the gold standard for diagnosing renal artery stenosis. Non-invasive imaging tests like ultrasound and CT angiography are now available, offering alternatives with discussed benefits and drawbacks.
Area of Science:
- Medical imaging
- Cardiovascular diagnostics
Background:
- Renal artery stenosis (RAS) diagnosis relies on angiography.
- Treatment efficacy confirms the significance of RAS diagnosis.
Purpose of the Study:
- To review non-invasive diagnostic methods for renal artery stenosis.
- To discuss the advantages and disadvantages of available non-invasive tests.
Main Methods:
- Review of current non-invasive imaging modalities.
- Comparative analysis of ultrasound, CT angiography, and MR angiography.
- Discussion of functional imaging techniques.
Main Results:
- Non-invasive methods for RAS diagnosis are now available.
- Each non-invasive test has specific merits and limitations.
- Angiography remains the definitive diagnostic standard.
Conclusions:
- Non-invasive imaging plays a crucial role in evaluating renal artery stenosis.
- Selection of the appropriate non-invasive test depends on clinical context.
- Further research may refine the utility of these diagnostic tools.
Related Concept Videos
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
Nephrons
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma happens...
Renal Corpuscle
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...
Continuous Renal Replacement Therapy
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
Acute Kidney Injury II: Pathophysiology
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
Diabetic Nephropathy
Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...

