Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

New diagnostic tests for pulmonary embolism.

J A Kline1, K L Johns, S A Colucciello

  • 1Department of Emergency Medicine, Carolinas Medical Center, Charlotte, NC 28232-2861, USA. jkline@carolinas.org

Annals of Emergency Medicine
|January 29, 2000
PubMed
Summary

A better screening tool for pulmonary embolism (PE) is needed in emergency departments. This study evaluates new diagnostic tests, including D-dimer and spiral CT, for diagnosing PE.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polyphenic risk score shows robust predictive ability for long-term future suicidality.

Discover mental health·2022
Same author

Ruling out pulmonary embolism across different subgroups of patients and healthcare settings: protocol for a systematic review and individual patient data meta-analysis (IPDMA).

Diagnostic and prognostic research·2019
Same author

Abdominal Trauma.

The Physician and sportsmedicine·2016
Same author

Treatment of submassive pulmonary embolism with tenecteplase or placebo: cardiopulmonary outcomes at 3 months: multicenter double-blind, placebo-controlled randomized trial.

Journal of thrombosis and haemostasis : JTH·2014
Same author

Thrombolysis for normotensive patients with acute symptomatic pulmonary embolism: a rebuttal.

Journal of thrombosis and haemostasis : JTH·2012
Same author

Autoimmune signals in non-segmental vitiligo patients are associated with distinct clinical parameters and toxic exposures.

Journal of the European Academy of Dermatology and Venereology : JEADV·2012

Area of Science:

  • Medical Diagnostics
  • Radiology
  • Pulmonary Medicine

Background:

  • The Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) study established the radioisotopic ventilation-perfusion (V/Q) lung scan as a key diagnostic tool for pulmonary embolism (PE).
  • Despite its widespread use, the V/Q scan's limitations necessitate the development of improved screening methods for emergency department (ED) settings.
  • Recent advancements have introduced novel imaging and laboratory tests for PE evaluation.

Purpose of the Study:

  • To assess the diagnostic utility of emerging tests for pulmonary embolism (PE).
  • To compare the effectiveness of D-dimer testing and alveolar dead space determination as screening tools.
  • To evaluate spiral computed tomography (CT), magnetic resonance imaging (MRI), and echocardiography as confirmatory tests for PE.

Related Experiment Videos

Main Methods:

  • Review of diagnostic utility for D-dimer, alveolar dead space, spiral CT, MRI, transthoracic echocardiography, and transesophageal echocardiography.
  • Inclusion of recent data on alveolar-arterial oxygen gradient and V/Q scan for comparative analysis.
  • Description of the potential application of these tests in a hypothetical emergency department (ED) population.

Main Results:

  • Emerging diagnostic modalities show promise for evaluating suspected pulmonary embolism (PE).
  • D-dimer tests and alveolar dead space determination are explored as potential screening tools.
  • Spiral CT, MRI, and echocardiography are assessed as confirmatory diagnostic methods for PE.

Conclusions:

  • Newer diagnostic tests offer potential improvements over traditional methods for pulmonary embolism (PE) diagnosis.
  • The evaluation of these tests is crucial for optimizing PE diagnosis in emergency departments.
  • Further research and application in clinical settings are warranted to establish the role of these novel tests.