Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Three dimensional registration of mechanical bladder activity using polystyrene fluorescent spheres: A technical

M V Kinder¹, R Bos, P J Willems

¹Department of Urology, Maastricht University Hospital, Maastricht, The Netherlands. M.kinder@pyramid.nl

Archives of Physiology and Biochemistry

|January 29, 2000

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Induction of Cure in Early Arthritis (I CEA): study protocol for an investigator-initiated randomized single-blind clinical trial with open-label extension to compare three treatment strategies in patients with newly diagnosed undifferentiated arthritis.

Trials·2024

Same author

Cost-effectiveness and cost-utility of add-on, low-dose prednisolone in patients with rheumatoid arthritis aged 65+: The pragmatic, multicenter, placebo-controlled GLORIA trial.

Seminars in arthritis and rheumatism·2022

Same author

[<sup>18</sup>F]Sodium Fluoride PET has the potential to identify active formation of calcinosis cutis in limited cutaneous systemic sclerosis.

Seminars in arthritis and rheumatism·2022

Same author

Remarkable international variability in reasons for ineligibility and non-participation in the GLORIA trial.

Scandinavian journal of rheumatology·2019

Same author

Open treatment of unilateral mandibular condyle fractures in adults: a systematic review.

International journal of oral and maxillofacial surgery·2017

Same author

Diseases due to unhealthy environments: an updated estimate of the global burden of disease attributable to environmental determinants of health.

Journal of public health (Oxford, England)·2016

This study demonstrates a novel optical marker tracing technique to measure bladder wall deformation in rabbits. The method successfully quantifies local contraction and relaxation during spontaneous activity and electrical nerve stimulation.

Area of Science:

Biomedical Engineering
Physiology
Urology

Background:

Optical marker tracing quantifies local material deformation in various tissues.
Previous applications include heart tissue, skin, and striated muscles.

Purpose of the Study:

To investigate the feasibility of optical marker tracing for quantifying rabbit bladder wall deformation in vivo.
To analyze bladder wall activity during spontaneous contractions and electrical nerve stimulation.

Main Methods:

Polystyrene fluorescent spheres (0.6 mm diameter) were attached to the rabbit bladder serosal wall.
Three-dimensional video registration of spheres tracked principal strains (ε1, ε2) on the bladder surface.
Measurements were taken during spontaneous activity and after electrical stimulation of sacral nerve root S2.

Related Experiment Videos

Main Results:

Spontaneous bladder activity showed asynchronous contraction/relaxation of principal strains.
Electrical stimulation synchronized ε1 and ε2, indicating coordinated contraction or relaxation.
Repeated stimulation reduced the coordination between principal strains.
The technique successfully identified local areas of contraction and relaxation.

Conclusions:

3D video registration of fluorescent spheres is a feasible technique for studying bladder wall dynamics in vivo.
The method can measure electrical stimulation effects and spontaneous bladder activity.
This technique allows for the identification of localized bladder wall contraction and relaxation patterns.