Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human embryonic stem cell and embryonic germ cell lines.

J A Thomson1, J S Odorico

  • 1Wisconsin Regional Primate Research Center, and Department of Surgery, School of Medicine (respectively), University of Wisconsin, 1223 Capitol Court, Madison, WI 53715-1299, USA. thomson@primate.wisc.edu

Trends in Biotechnology
|February 1, 2000
PubMed
Summary

Human embryonic stem (ES) cells and embryonic germ (EG) cells can be indefinitely cultured while retaining their potential to form various cell types. These cells offer new models for tissue research, drug discovery, and regenerative therapies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

OPTN/SRTR 2017 Annual Data Report: Pancreas.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2019
Same author

Love-Lights.

The Hospital·2018
Same author

Impact of ureteral stricture and treatment choice on long-term graft survival in kidney transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2018
Same author

A Single-Center Experience With Tacrolimus LCP (Envarsus XR) in Pancreas Transplant Recipients.

The Annals of pharmacotherapy·2017
Same author

Broadened Allocation of Pancreas Transplants Across Compatible ABO Blood Types.

Transplantation proceedings·2017
Same author

Fabrication and Characterization of Electrospun Thermoplastic Polyurethane/Fibroin Small-Diameter Vascular Grafts for Vascular Tissue Engineering.

International polymer processing : the journal of the Polymer Processing Society·2017

Area of Science:

  • Stem cell biology
  • Developmental biology
  • Regenerative medicine

Background:

  • Human embryonic stem (ES) cells and embryonic germ (EG) cells are pluripotent cell types.
  • These cells possess the capacity for indefinite self-renewal.
  • They can differentiate into virtually all cell types of the human body.

Purpose of the Study:

  • To highlight the significance of human ES and EG cells in biological research.
  • To explore their potential applications in drug discovery and testing.
  • To discuss their promise for novel cell-based transplantation therapies.

Main Methods:

  • Culturing of undifferentiated human embryonic stem (ES) cells.
  • Culturing of undifferentiated human embryonic germ (EG) cells.

Related Experiment Videos

  • Assessment of pluripotency and differentiation potential.

    • Main Results:

    • Demonstrated indefinite culturability of human ES and EG cells.
    • Confirmed the maintenance of pluripotency and differentiation potential.
    • Established these cells as a viable model system.

    Conclusions:

    • Human ES and EG cells are valuable tools for studying human development and tissue function.
    • These cells offer innovative strategies for pharmaceutical research and development.
    • Significant therapeutic potential exists for ES and EG cell-derived tissues in regenerative medicine.