Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Asthma and asthma-like disorders.

O Löwhagen1

  • 1Allergy Centre, Sahlgrenska University Hospital, Göteborg, Sweden.

Respiratory Medicine
|February 1, 2000
PubMed
Summary

Diagnosing bronchial asthma can be challenging due to varied symptoms and lack of a gold standard. This review highlights asthma-like conditions, such as sensory hyper-reactivity, which require further research for effective treatments.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Physiotherapy in asthma using the new Lotorp method.

Complementary therapies in clinical practice·2014
Same author

Diagnosis of asthma - a new approach.

Allergy·2012
Same author

Early and late phase asthmatic response in lower airways of cat-allergic asthmatic patients--a comparison between experimental and environmental allergen challenge.

Allergy·2007
Same author

Perception of what?

The European respiratory journal·2005
Same author

Haplotypes of the interleukin-4 receptor alpha chain gene associate with susceptibility to and severity of atopic asthma.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2004
Same author

Allergen specific immunotherapy attenuates early and late phase reactions in lower airways of birch pollen asthmatic patients: a double blind placebo-controlled study.

Allergy·2003

Area of Science:

  • Pulmonology
  • Allergy and Immunology
  • Respiratory Medicine

Background:

  • Bronchial asthma is a chronic inflammatory airway disease with reversible obstruction.
  • Accurate asthma diagnosis is difficult due to symptom variability, medication interference, and lack of a gold standard.
  • Asthma-like symptoms are increasingly recognized, necessitating differentiation from classical asthma.

Purpose of the Study:

  • To present and discuss differential diagnoses for patients presenting with asthma-like symptoms, particularly in adults.
  • To highlight conditions that mimic asthma, aiding clinicians in accurate diagnosis.
  • To emphasize the need for research into non-asthmatic conditions with similar presentations.

Main Methods:

  • Review of literature and clinical observations regarding asthma and asthma-like disorders.
  • Discussion of common differential diagnoses encountered in asthma and allergy clinics.
  • Exploration of diagnostic challenges and potential new diagnostic tools, like the capsaicin inhalation test for sensory hyper-reactivity.

Main Results:

  • Common differential diagnoses for asthma-like symptoms include Chronic Obstructive Pulmonary Disease (COPD), nonasthmatic cough, and Sensory Hyper-Reactivity (SHR).
  • Sensory Hyper-Reactivity (SHR) shares symptom and trigger similarities with asthma, often leading to misdiagnosis.
  • A capsaicin inhalation test is proposed as a potential objective diagnostic method for SHR.

Conclusions:

  • Accurate diagnosis of asthma is complicated by overlapping symptoms with other respiratory conditions.
  • Conditions like SHR present significant diagnostic challenges and currently lack effective therapeutic options.
  • Further research into the pathophysiology of asthma-like disorders is crucial for developing targeted treatments.

Related Experiment Videos