Related Experiment Video
Updated: Jul 18, 2026

Quantification of Orofacial Phenotypes in Xenopus
Published on: November 6, 2014
Craniofacial growth in complete unilateral cleft lip and palate: a roentgeno-cephalometric study
Abstract:
This study investigated craniofacial growth in unilateral complete clefts using lateral roentgenographic cephalograms. The cleft sample was composed of 135 males and 120 females aged four, six, eight, ten, twelve and eighteen years. Control subjects included 120 non-cleft males and 120 non-cleft females of similar age to the cleft subjects. The cleft group differed from the control group in several major respects: (1) Their over-all growth trend showed a more downward or vertical direction; (2) The cranial base angle was more flattened; (3) The maxilla was smaller and was located in a more posterior and upward position; (4) Ramal height was shorter and the gonial angle was more obtuse. Chin position was generally retrognathic; (5) Skeletal profile showed less convexity; (6) Upper face height was less and lower face height was greater; (7) Both upper and lower central incisors showed a marked lingual inclination; (8) Females in both groups matured about two years earlier than did males. Underdevelopment in both the maxilla and the mandible was more pronounced in cleft females than in cleft males.
Related Concept Videos
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...

