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Will there be resistance to the RECIST (Response Evaluation Criteria in Solid Tumors)?

E A Gehan, M C Tefft

    Journal of the National Cancer Institute
    |February 3, 2000
    PubMed
    Abstract

    No abstract available in PubMed .

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    Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

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