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Infectious crystalline keratopathy.

N Sharma¹, R B Vajpayee, N Pushker

¹Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi.

The CLAO Journal : Official Publication of the Contact Lens Association of Ophthalmologists, Inc

|February 3, 2000

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Infectious crystalline keratopathy (ICK) is a slow-progressing corneal infection characterized by unique stromal opacities. Early diagnosis and treatment, often involving antibiotics and steroid withdrawal, are crucial for preserving vision.

Area of Science:

Ophthalmology
Infectious Diseases
Corneal Pathology

Background:

Infectious crystalline keratopathy (ICK) presents as a distinct indolent corneal infection.
Characterized by needle-like, branching crystalline opacities within the corneal stroma.
Typically occurs without significant corneal or anterior segment inflammation.

Purpose of the Study:

To comprehensively review the diagnosis of ICK.
To detail the microbial and pathological features of ICK.
To elucidate the pathogenesis and treatment strategies for ICK.

Main Methods:

A thorough review of existing medical literature on infectious crystalline keratopathy.
Analysis of case studies and research articles pertaining to ICK.

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Main Results:

ICK is an indolent corneal infection.
Key features include crystalline opacities in the corneal stroma.
Often a complication of corneal surgery and keratitis, commonly caused by alpha-hemolytic Streptococcus.

Conclusions:

Treatment may involve discontinuing topical steroids and initiating aggressive antibiotic therapy.
Persistent infection, vascularization, or scarring can impair visual acuity.
Penetrating keratoplasty may be necessary in severe or refractory cases.