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Agrochelin, a new cytotoxic antibiotic from a marine Agrobacterium. Taxonomy, fermentation, isolation,
C Acebal1, L M Cañedo, J L Puentes
1Instituto Biomar S.A. Pol. Ind. de Leon. Edif. CEI, Onzonilla, León, Spain.
The Journal of Antibiotics
|February 3, 2000
Abstract:
Agrochelin, a new alkaloid cytotoxic substance, was produced by the fermentation of Agrobacterium sp. The compound was obtained from the bacterial cells by solvent extraction and purified by silica gel chromatography. Agrochelin (1) and its acetyl derivative (2) exhibited cytotoxic activity.