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Is Crohn's disease rare in India?
1Gastroenterology Unit, Kasturba Medical College Hospital, Manipal. info@mahe.ernet.in
Summary
Crohn's disease may not be rare in India. High rates of intestinal tuberculosis might lead to under-recognition of Crohn's disease, impacting patient diagnosis and care.
Area of Science:
- Gastroenterology
- Internal Medicine
- Inflammatory Bowel Disease Research
Background:
- Crohn's disease (CD) is historically considered rare in India.
- This perception may stem from diagnostic challenges and potential under-recognition.
Purpose of the Study:
- To analyze patient data for Crohn's disease (CD) at a tertiary referral center.
- To assess the prevalence and characteristics of CD in an Indian population.
Main Methods:
- Retrospective analysis of chronic inflammatory bowel disease patients over 5 years.
- Diagnosis of CD based on clinical, histological, and exclusion criteria.
- Evaluation of disease presentation, involvement, and treatment response.
Main Results:
- 25 patients diagnosed with Crohn's disease (CD), mean age 31.7 years.
- Common symptoms included abdominal pain (84%) and diarrhea (80%).
- Ileocecal and colonic involvement were frequent; granulomas found in 48% of biopsies.
Conclusions:
- Crohn's disease (CD) may be more prevalent in India than previously thought.
- High prevalence of intestinal tuberculosis could lead to misdiagnosis or under-recognition of CD.
- Further research is needed to understand the true incidence and diagnostic challenges of CD in India.