Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Superficial doses from serial tomotherapy delivery.

S Mutic1, D A Low

  • 1Radiation Oncology Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri 63110, USA. mutic_s@castor.wustl.edu

Medical Physics
|February 5, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute impact of aerobic exercise on local cutaneous thermal hyperaemia.

Microvascular research·2022
Same author

The effects of exercise training in the cold on cerebral blood flow and cerebrovascular function in young healthy individuals.

Autonomic neuroscience : basic & clinical·2022
Same author

An Adaptive Low-Rank Modeling-Based Active Learning Method for Medical Image Annotation.

Ingenierie et recherche biomedicale : IRBM = Biomedical engineering and research·2021
Same author

Oxynet: A collective intelligence that detects ventilatory thresholds in cardiopulmonary exercise tests.

European journal of sport science·2020
Same author

A mechanistic study of the tremor associated with epidural anaesthesia for intrapartum caesarean delivery.

International journal of obstetric anesthesia·2020
Same author

McSART: an iterative model-based, motion-compensated SART algorithm for CBCT reconstruction.

Physics in medicine and biology·2019
Same journal

Correction to "On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity".

Medical physics·2026
Same journal

Multi-view constrained semi-supervised vertebra detection for 3D ultrasound spine volume.

Medical physics·2026
Same journal

Accuracy of quantitative <sup>177</sup>Lu SPECT/CT imaging: A systematic review.

Medical physics·2026
Same journal

Physics-constrained dual-domain network for CBCT reconstruction from orthogonal X-rays in gynecologic radiotherapy.

Medical physics·2026
Same journal

Decomposition-based harmonization for quantitative PET imaging across scanners and radiotracers.

Medical physics·2026
Same journal

Development and evaluation of an in vivo dose-based monitoring system for electron FLASH radiation therapy.

Medical physics·2026
See all related articles

Serial tomotherapy delivers radiation in slices, potentially altering superficial doses compared to conventional methods. This study found measured doses slightly exceeded calculated ones, with superficial targets requiring bolus for accurate surface delivery.

Area of Science:

  • Radiation Oncology
  • Medical Physics

Background:

  • Serial tomotherapy utilizes sequential irradiation slices and patient movement.
  • This delivery method may cause superficial dose variations compared to conventional radiation therapy.

Purpose of the Study:

  • To investigate superficial depth-dose distributions in serial tomotherapy.
  • To compare measured doses with calculated doses for geometric target volumes.

Main Methods:

  • Experimental investigation using cylindrical target volumes in a water-equivalent phantom.
  • Dose measurements at superficial depths using thermoluminescent dosimetry chips.
  • Treatment plans simulated for centrally located, off-centered, and superficial targets.

Main Results:

Related Experiment Videos

  • Measured superficial doses were slightly greater than calculated doses across all target configurations.
  • For superficial targets, measured doses in the buildup region indicated a need for bolus.
  • Serial tomotherapy dose delivery differs from conventional techniques, especially superficially.

Conclusions:

  • Bolus material is necessary for superficial targets to achieve prescribed surface doses in serial tomotherapy.
  • Accurate superficial dose assessment is crucial for intensity-modulated radiation therapy planning with this technique.