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Reliability of water proton chemical shift temperature calibration for focused ultrasound ablation therapy
T Wu1, K R Kendell, J P Felmlee
1Department of Diagnostic Radiology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA. wu.tao@mayo.edu
Abstract:
Our purpose in this work was to assess the reliability of the calibration coefficient for magnetic resonance water proton chemical shift temperature mapping. Over a six month period, the calibration coefficient was measured 15 times in several different phantoms. A highly linear relationship between water proton chemical shift and temperature change was found. The average temperature calibration coefficient determined from all studies was 0.009+/-0.001 ppm/degrees C. Four of the 15 studies were conducted on the same day using the same phantom. The average temperature calibration coefficient of these four studies was 0.0096+/-0.0001 ppm/degrees C.