[Studies on the pharmacodynamics and compatibility of the local anesthetic carticain]

Two local anesthetics were compared with a placebo with regard to subjective tolerance and influence on driving capacity in a double blind test in eight male probands. Neither performance, the ability to respond, reactivity, nor fine motor coordination were reduced or impaired five to sixty minutes after a submucous injection of 3.6 ml of the local anesthetics tested. There were no changes of self-evaluation in the sense of a changed active-passive polarity.