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[Antimycotic therapy in otomycosis with tympanic membrane perforation]
G Dyckhoff1, T Hoppe-Tichy, R Kappe
1Universitäts-HNO-Klinik Heidelberg (Arztlicher Direktor: Prof. Dr. H. Weidauer).
Abstract:
Especially after prolonged antibiotic ototopic therapy otomycosis is not rare. An inoculation of fungi into the tympanic cavity however may have serious sequelae. Therefore an eradication of fungi from the external auditory canal is imperative before surgery. In addition to thorough cleaning of the outer ear canal antimycotic preparations are recommended in treating otomycosis. However, all of the commercially available ear drops contain ototoxic agents. In the case of defects of the tympanic membrane a damage of the inner ear may result. Alternatively, we suggest an aqueous solution of Miconazol 0,5%.
Insights
Otomycosis, a fungal ear infection, can occur after prolonged antibiotic use. An aqueous solution of Miconazole 0.5% is proposed as a safe alternative to ototoxic ear drops for treating external ear canal infections.
Area of Science:
- Otolaryngology
- Mycology
- Pharmacology
Context:
- Otomycosis, a fungal infection of the ear, is a common complication following extended topical antibiotic therapy.
- Fungal inoculation into the tympanic cavity can lead to severe complications.
- Eradication of external auditory canal fungi is crucial before surgical intervention.
Purpose:
- To address the ototoxicity of current antimycotic ear drops used for otomycosis.
- To propose a safer alternative treatment for fungal ear infections, particularly in cases with tympanic membrane defects.
Summary:
- Current treatments for otomycosis often involve ear drops containing ototoxic agents, posing a risk of inner ear damage, especially with tympanic membrane perforations.
- Thorough cleaning of the ear canal combined with antimycotic preparations is standard practice.
- An aqueous solution of Miconazole 0.5% is presented as a potentially safer alternative.
Impact:
- Highlights the ototoxic risks associated with conventional otomycosis treatments.
- Suggests a viable, less harmful therapeutic option for otomycosis management.
- Emphasizes the importance of safe and effective treatment to prevent inner ear damage.